Displaying items by tag: Pharmacology
Medicines can have different effects in children than in adults, which is not just a question of the right dose. Yet, still only few pharmaceuticals have been specifically tested and approved for this patient group. For treatment of thrombosis, children currently receiv Heparin and Vitamin K antagonists which are problematic and not approved for children. A recent international study investigate the anticoagulant Rivaroxaban approved for adults in children with acute venous thromboembolism.
Vaginal yeast infections may occur more commonly during pregnancy, and most are treated with topical medications, or creams. Oral medications are prescribed when topical treatment fails, but the safety of such agents during pregnancy is controversial. A recent review and analysis examined all relevant studies published on this topic.
The proportion of people aged over 65 on antidepressants has more than doubled in two decades – according to new research led by the University of East Anglia.
Despite a rise in antidepressant use, there was little change in the number of older people diagnosed with depression.
Antidepressants are generally safe, according to a new study by an international team of researchers. By assessing evidence from 45 meta-analyses, which combined the results from many studies, the researchers did not find strong evidence of adverse health outcomes associated with antidepressant use. The findings have been published in JAMA Psychiatry.
A team of researchers of MedUni Vienna working with the endocrinologists and gender physicians Michael Leutner and Alexandra Kautzky-Willer as well the division for complex statistical systems with Peter Klimek and Caspar Matzhold in cooperation with Complexity Science Hub Vienna were able to demonstrate for the first time a connection between the potency and dosage of statins with a diagnosis of osteoporosis, based on several million data sets. Essential result: the higher the dosage, the greater the likelihood of osteoporosis. The study was published in the top journal "Annals of the Rheumatic Diseases".
When children with ADHD don’t respond well to Methylphenidate doctors often increase the dose. Now a new review shows that increasing the dose may not always be the best option, as it may have no effect on some of the functional impairments associated with ADHD.